Aharoni A, Keizer LC, Bouwmeester HJ, Sun Z, Alvarez-Huerta M, Verhoeven HA, Blaas J, van Houwelingen AM, De Vos RC, van Der Voet H, Jansen RC, Guis M, Mol J, Davis RW, Schena M, van Tunen AJ, O'Connell AP 2000 Identification of the SAAT gene involved in strawberry flavor biogenesis by use of DNA microarrays. Plant Cell 12: 647-662.

Akhtar M, Stevenson DE, Gani D 1990 Fern L-methionine decarboxylase: kinetics and mechanism of decarboxylation and abortive transamination. Biochemistry 29: 7648-7660.

Alawady AE, Grimm B 2005 Tobacco Mg protoporphyrin IX methyltransferase is involved in inverse activation of Mg porphyrin and protoheme synthesis. Plant J. 41: 282-290.

Arite T, Iwata H, Ohshima K, Maekawa M, Nakajima M, Kojima M, Sakakibara H, Kyozuka J 2007 DWARF10, an RMS1/MAX4/DAD1 ortholog, controls lateral bud outgrowth in rice. Plant J. 51: 1019-1029.

Azevedo RA, Arruda P, Turner WL, Lea PJ 1997 The biosynthesis and metabolism of the aspartate derived amino acids in higher plants. Phytochemistry 46: 395-419.

Bailey NJ, Oven M, Holmes E, Nicholson JK, Zenk MH 2003 Metabolomic analysis of the consequences of cadmium exposure in Silene cucubalus cell cultures via 1H NMR spectroscopy and chemometrics. Phytochemistry 62: 851-858.

Barbagallo RP, Oxborough K, Pallett KE, Baker NR 2003 Rapid, noninvasive screening for perturbations of metabolism and plant growth using chlorophyll fluorescence imaging. Plant Physiol. 132: 485-493.

Baskin TI, Bivens NJ 1995 Stimulation of radial expansion in Arabidopsis roots by inhibitors of actomyosin and vesicle secretion but not by various inhibitors of metabolism. Planta 197: 514-521.

Basso AL, Ricca E, Caruso C, Ferrara L, De Felice M 1993 Acetohydroxy acid synthase and threonine deaminase activities, and the biosynthesis of isoleucine-leucine-valine in Streptococcus bovis. Res. Microbiol. 144: 539-545.

Belitsky BR, Gustafsson MC, Sonenshein AL, Von Wachenfeldt C 1997 An lrp-like gene of Bacillus subtilis involved in branched-chain amino acid transport. J. Bacteriol. 179: 5448-5457.

Biou V, Dumas R, Cohen-Addad C, Douce R, Job D, Pebay-Peyroula E 1997 The crystal structure of plant acetohydroxy acid isomeroreductase complexed with NADPH, two magnesium ions and a herbicidal transition state analog determined at 1.65 A resolution. EMBO J. 16: 3405-3415.

Blauth SL, Kim KN, Klucinec J, Shannon JC, Thompson D, Guiltinan M 2002 Identification of Mutator insertional mutants of starch-branching enzyme 1 (sbe1) in Zea mays L. Plant Mol. Biol. 48: 287-297.

Bonner CA, Fischer RS, Ahmad S, Jensen RA 1990 Remnants of an ancient pathway to L-phenylalanine and L-tyrosine in enteric bacteria: evolutionary implications and biotechnological impact. Appl. Environ. Microbiol. 56: 3741-3747.

Broeckling CD, Huhman DV, Farag MA, Smith JT, May GD, Mendes P, Dixon RA, Sumner LW 2005 Metabolic profiling of Medicago truncatula cell cultures reveals the effects of biotic and abiotic elicitors on metabolism. J. Exp. Bot. 56: 323-336.

Cavin JF, Dartois V, Labarre C, Divies C 1999 Cloning of branched chain amino acid biosynthesis genes and assays of alpha-acetolactate synthase activities in Leuconostoc mesenteroides subsp. cremoris. Res. Microbiol. 150: 189-198.

Chang AK, Duggleby RG 1998 Herbicide-resistant forms of Arabidopsis thaliana acetohydroxyacid synthase: characterization of the catalytic properties and sensitivity to inhibitors of four defined mutants. Biochem. J. 333: 765-777.

Chang AK, Duggleby RG 1997 Expression, purification and characterization of Arabidopsis thaliana acetohydroxyacid synthase. Biochem. J. 327: 161-169.

Chang YY, Wang AY, Cronan JE Jr 1993 Molecular cloning, DNA sequencing, and biochemical analyses of Escherichia coli glyoxylate carboligase. An enzyme of the acetohydroxy acid synthase-pyruvate oxidase family. J. Biol. Chem. 268: 3911-3919.

Chinchilla D, Schwarz FP, Eisenstein E 1998 Amino acid substitutions in the C-terminal regulatory domain disrupt allosteric effector binding to biosynthetic threonine deaminase from Escherichia coli. J. Biol. Chem. 273: 23219-23224.

Chipman D, Barak Z, Schloss JV 1998 Biosynthesis of 2-aceto-2-hydroxy acids: acetolactate synthases and acetohydroxyacid synthases. Biochim. Biophys. Acta 1385: 401-419.

Craster HL, Potter CA, Baumberg S 1999 End-product control of expression of branched-chain amino acid biosynthesis genes in Streptomyces coelicolor A3(2): paradoxical relationships between DNA sequence and regulatory phenotype. Microbiology 145: 2375-2384.

Cummins I, Landrum M, Steel PG, Edwards R 2007 Structure activity studies with xenobiotic substrates using carboxylesterases isolated from Arabidopsis thaliana. Phytochemistry 68: 811-818.

Curic M, Stuer-Lauridsen B, Renault P, Nilsson D 1999 A general method for selection of alpha-acetolactate decarboxylase-deficient Lactococcus lactis mutants to improve diacetyl formation. Appl. Environ. Microbiol. 65: 1202-1206.

Daschner K, Thalheim C, Guha C, Brennicke A, Binder S 1999 In plants a putative isovaleryl-CoA-dehydrogenase is located in mitochondria. Plant Mol. Biol. 39: 1275-1282.

Davoodi J, Drown PM, Bledsoe RK, Wallin R, Reinhart GD, Hutson SM 1998 Overexpression and characterization of the human mitochondrial and cytosolic branched-chain aminotransferases. J. Biol. Chem. 273: 4982-4989.

De Bellis L, Gonzali S, Alpi A, Hayashi H, Hayashi M, Nishimura M 2000 Purification and characterization of a novel pumpkin short-chain acyl-coenzyme A oxidase with structural similarity to acyl-coenzyme A dehydrogenases. Plant Physiol. 123: 327-334.

De Boer M, Bebelman JP, Goncalves PM, Maat J, Van Heerikhuizen H, Planta RJ 1998 Regulation of expression of the amino acid transporter gene BAP3 in Saccharomyces cerevisiae. Mol. Microbiol. 30: 603-613.

De Rossi E, Leva R, Gusberti L, Manachini PL, Riccardi G 1995 Cloning, sequencing and expression of the ilvBNC gene cluster from Streptomyces avermitilis. Gene 166: 127-132.

De Veylder L, Van Montagu M, Inze D 1997 Herbicide safener-inducible gene expression in Arabidopsis thaliana. Plant Cell Physiol. 38: 568-577.

de Vienne D, Bost B, Fievet J, Dillmann C 2001 Optimisation of enzyme concentrations for unbranched reaction chains: the concept of combined response coefficient. Acta Biotheor. 49: 341-350.

Dewaele E, Forlani G, Degrande D, Nielsen E, Rambour S 1997 Biochemical characterization of chlorsulfuron resistance in Cichorium intybus L var Witloof. J. Plant Physiol. 151: 109-114.

Didion T, Grausland M, Kielland-Brandt C, Andersen HA 1996 Amino acids induce expression of BAP2, a branched-chain amino acid permease gene in Saccharomyces cerevisiae. J. Bacteriol. 178: 2025-2029.

Diebold R, Schuster J, Daschner K, Binder S 2002 The branched-chain amino acid transaminase gene family in Arabidopsis encodes plastid and mitochondrial proteins. Plant Physiol. 129: 540-550.

Dobson CM, Gradinger A, Longo N, Wu X, Leclerc D, Lerner-Ellis J, Lemieux M, Belair C, Watkins D, Rosenblatt DS, Gravel RA 2006 Homozygous nonsense mutation in the MCEE gene and siRNA suppression of methylmalonyl-CoA epimerase expression: a novel cause of mild methylmalonic aciduria. Mol. Genet. Metab. 88: 327-333.

Doering CB, Williams IR, Danner DJ 2000 Controlled overexpression of BCKD kinase expression: metabolic engineering applied to BCAA metabolism in a mammalian system. Metab. Eng. 2: 349-356.

Donadini R, Copeland L 2000 Acetohydroxy acid reductoisomerase of wheat. Aust. J. Plant Physiol. 27: 417-423.

Duggleby RG 1997 Identification of an acetolactate synthase small subunit gene in two eukaryotes. Gene 190: 245-249.

Duggleby RG, Pang SS, Yu H, Guddat LW 2003 Systematic characterization of mutations in yeast acetohydroxyacid synthase. Interpretation of herbicide-resistance data. Eur. J. Biochem. 270: 2895-2904.

Dumas R, Cornillon-Bertrand C, Guigue-Talet P, Genix P, Douce R, Job D 1994 Interactions of plant acetohydroxy acid isomeroreductase with reaction intermediate analogues: correlation of the slow, competitive, inhibition kinetics of enzyme activity and herbicidal effects. Biochem. J. 301: 813-820.

Dumas R, Curien G, DeRose RT, Douce R 1993 Branched-chain-amino-acid biosynthesis in plants: molecular cloning and characterization of the gene encoding acetohydroxy acid isomeroreductase (ketol-acid reductoisomerase) from Arabidopsis thaliana (thale cress). Biochem. J. 294: 821-828.

Dumas R, Job D, Douce R, Pebay-Peyroula E, Cohen-Addad C 1994 Crystallization and preliminary crystallographic data for acetohydroxy acid isomeroreductase from Spinacia oleracea. J. Mol. Biol. 242: 578-581.

Dumas R, Job D, Ortholand JY, Emeric G, Greiner A, Douce R 1992 Isolation and kinetic properties of acetohydroxy acid isomeroreductase from spinach (Spinacia oleracea) chloroplasts overexpressed in Escherichia coli. Biochem. J. 288: 865-874.

Dumontet C, Roch AM, Quash G 1996 Methionine dependence of tumor cells: programmed cell survival? Oncol. Res. 8: 469-471.

Eden A, Benvenisty N 1998 Characterization of a branched-chain amino-acid aminotransferase from Schizosaccharomyces pombe. Yeast 14: 189-194.

Ekena K, Liao MK, Maloy S 1990 Activation of a new proline transport system in Salmonella typhimurium. J. Bacteriol. 172: 2940-2945.

Epelbaum S, Chipman DM, Barak Z 1996 Metabolic effects of inhibitors of two enzymes of the branched-chain amino acid pathway in Salmonella typhimurium. J. Bacteriol. 178: 1187-1196.

Epelbaum S, LaRossa RA, VanDyk TK, Elkayam T, Chipman DM, Barak Z 1998 Branched-chain amino acid biosynthesis in Salmonella typhimurium: a quantitative analysis. J. Bacteriol. 180: 4056-4067.

Ernsting BR, Atkinson MR, Ninfa AJ, Matthews RG 1992 Characterization of the regulon controlled by the leucine-responsive regulatory protein in Escherichia coli. J. Bacteriol. 174: 1109-1118.

Farag MA, Ryu CM, Sumner LW, Pare PW 2006 GC-MS SPME profiling of rhizobacterial volatiles reveals prospective inducers of growth promotion and induced systemic resistance in plants. Phytochemistry 67: 2262-2268.

Faure M, Glomot F, Bledsoe R, Hutson S, Papet I 1999 Purification and cloning of the mitochondrial branched-chain amino acid aminotransferase from sheep placenta. Eur. J. Biochem. 259: 104-111.

Feild MJ, Nguyen DC, Armstrong FB 1989 Amino acid sequence of Salmonella typhimurium branched-chain amino acid aminotransferase. Biochemistry 28: 5306-5310.

Forlani G, Suardi MC, Nielsen E 1996 Deregulated branched-chain amino acid synthesis in a Nicotiana plumbaginifolia cell line resistant to valine. Plant Growth Regul. 19: 241-248.

Forsberg H, Gilstring CF, Zargari A, Martinez P, Ljungdahl PO 2001 The role of the yeast plasma membrane SPS nutrient sensor in the metabolic response to extracellular amino acids. Mol. Microbiol. 42: 215-228.

Friden P, Schimmel P 1988 LEU3 of Saccharomyces cerevisiae activates multiple genes for branched-chain amino acid biosynthesis by binding to a common decanucleotide core sequence. Mol. Cell Biol. 8: 2690-2697.

Fries M, Chauhan HJ, Domingo GJ, Jung HI, Perham RN 2003 Site-directed mutagenesis of a loop at the active site of E1 (alpha2beta2) of the pyruvate dehydrogenase complex. A possible common sequence motif. Eur. J. Biochem. 270: 861-870.

Funke RP, Kovar JL, Logsdon JM Jr, Corrette-Bennett JC, Straus DR, Weeks DP 1999 Nucleus-encoded, plastid-targeted acetolactate synthase genes in two closely related chlorophytes, Chlamydomonas reihardtii and Volvox carteri: phylogenetic origins and recent insertion of introns. Mol. Gen. Genet. 262: 12-21.

Gaston S, Ribas-Carbo M, Busquets S, Berry JA, Zabalza A, Royuela M 2003 Changes in mitochondrial electron partitioning in response to herbicides inhibiting branched-chain amino acid biosynthesis in soybean. Plant Physiol. 133: 1351-1359.

Goupil-Feuillerat N, Cocaign-Bousquet M, Godon JJ, Ehrlich SD, Renault P 1997 Dual role of alpha-acetolactate decarboxylase in Lactococcus lactis subsp. lactis. J. Bacteriol. 179: 6285-6293.

Graham IA, Eastmond PJ 2002 Pathways of straight and branched chain fatty acid catabolism in higher plants. Prog. Lipid Res. 41: 156-181.

Grandoni JA, Marta PT, Schloss JV 1998 Inhibitors of branched-chain amino acid biosynthesis as potential antituberculosis agents. J. Antimicrob. Chemother. 42: 475-482.

Guedon E, Serror P, Ehrlich SD, Renault P, Delorme C 2001 Pleiotropic transcriptional repressor CodY senses the intracellular pool of branched-chain amino acids in Lactococcus lactis. Mol. Microbiol. 40: 1227-1239.

Halgand F, Dumas R, Biou V, Andrieu JP, Thomazeau K, Gagnon J, Douce R, Forest E 1999 Characterization of the conformational changes of acetohydroxy acid isomeroreductase induced by the binding of Mg2+ ions, NADPH, and a competitive inhibitor. Biochemistry 38: 6025-6034.

Halgand F, Vives F, Dumas R, Biou V, Andersen J, Andrieu JP, Cantegril R, Gagnon J, Douce R, Forest E, Job D 1998 Kinetic and mass spectrometric analyses of the interactions between plant acetohydroxy acid isomeroreductase and thiadiazole derivatives. Biochemistry 37: 4773-4781.

Hanashiro I, Itoh K, Kuratomi Y, Yamazaki M, Igarashi T, Matsugasako J, Takeda Y 2008 Granule-bound starch synthase I is responsible for biosynthesis of extra-long unit chains of amylopectin in rice. Plant Cell Physiol. 49: 925-933.

Hattori J, Brown D, Mourad G, Labbe H, Ouellet T, Sunohara G, Rutledge R, King J, Miki B 1995 An acetohydroxy acid synthase mutant reveals a single site involved in multiple herbicide resistance. Mol. Gen. Genet. 246: 419-425.

Hazelwood LA, Tai SL, Boer VM, de Winde JH, Pronk JT, Daran JM 2006 A new physiological role for Pdr12p in Saccharomyces cerevisiae: export of aromatic and branched-chain organic acids produced in amino acid catabolism. FEMS Yeast Res. 6: 937-945.

Heath C, Jeffries AC, Hough DW, Danson MJ 2004 Discovery of the catalytic function of a putative 2-oxoacid dehydrogenase multienzyme complex in the thermophilic archaeon Thermoplasma acidophilum. FEBS Lett. 577: 523-527.

Hershey HP, Schwartz LJ, Gale JP, Abell LM 1999 Cloning and functional expression of the small subunit of acetolactate synthase from Nicotiana plumbaginifolia. Plant Mol. Biol. 40: 795-806.

Hill CM, Duggleby RG 1998 Mutagenesis of Escherichia coli acetohydroxyacid synthase isoenzyme II and characterization of three herbicide-insensitive forms. Biochem. J. 335: 653-661.

Hill CM, Duggleby RG 1999 Purified recombinant Escherichia coli ketol-acid reductoisomerase is unsuitable for use in a coupled assay of acetohydroxyacid synthase activity due to an unexpected side reaction. Protein Expr. Purif. 15: 57-61.

Hill CM, Pang SS, Duggleby RG 1997 Purification of Escherichia coli acetohydroxyacid synthase isoenzyme II and reconstitution of active enzyme from its individual pure subunits. Biochem. J. 327: 891-898.

Hofer T, Heinrich R 1993 A second-order approach to metabolic control analysis. J. Theor. Biol. 164: 85-102.

Hofmeyr JH 1986 Steady-state modelling of metabolic pathways: a guide for the prospective simulator. Comput. Appl. Biosci. 2: 5-11.

Hu Y, Cooper TG, Kohlhaw GB 1995 The Saccharomyces cerevisiae Leu3 protein activates expression of GDH1, a key gene in nitrogen assimilation. Mol. Cell Biol. 15: 52-57.

Hutson SM, Berkich D, Drown P, Xu B, Aschner M, LaNoue KF 1998 Role of branched-chain aminotransferase isoenzymes and gabapentin in neurotransmitter metabolism. J. Neurochem. 71: 863-874.

Hutson SM, Bledsoe RK, Hall TR, Dawson PA 1995 Cloning and expression of the mammalian cytosolic branched chain aminotransferase isoenzyme. J. Biol. Chem. 270: 30344-30352.

Ikeda H, Esaki N, Nakai S, Hashimoto K, Uesato S, Soda K, Fujita T 1991 Acyclic monoterpene primary alcohol:NADP+ oxidoreductase of Rauwolfia serpentina cells: the key enzyme in biosynthesis of monoterpene alcohols. J. Biochem. (Tokyo) 109: 341-347.

Inngjerdingen KT, Kiyohara H, Matsumoto T, Petersen D, Michaelsen TE, Diallo D, Inngjerdingen M, Yamada H, Paulsen BS 2007 An immunomodulating pectic polymer from Glinus oppositifolius. Phytochemistry 68: 1046-1058.

Inoue K, Kuramitsu S, Aki K, Watanabe Y, Takagi T, Nishigai M, Ikai A, Kagamiyama H 1988 Branched-chain amino acid aminotransferase of Escherichia coli: overproduction and properties. J. Biochem. (Tokyo) 104: 777-784.

Jarai G, Yagmai B, Fu YH, Marzluf GA 1990 Regulation of branched-chain amino acid biosynthesis in Neurospora crassa: cloning and characterization of the leu-1 and ilv-3 genes. Mol. Gen. Genet. 224: 383-388.

Jhee KH, Yoshimura T, Miles EW, Takeda S, Miyahara I, Hirotsu K, Soda K, Kawata Y, Esaki N 2000 Stereochemistry of the transamination reaction catalyzed by aminodeoxychorismate lyase from Escherichia coli: close relationship between fold type and stereochemistry. J. Biochem. (Tokyo) 128: 679-686.

Joutel A, Ducros A, Alamowitch S, Cruaud C, Domenga V, Marechal E, Vahedi K, Chabriat H, Bousser MG, Tournier-Lasserve E 1996 A human homolog of bacterial acetolactate synthase genes maps within the CADASIL critical region. Genomics 38: 192-198.

Junk DJ, Mourad GS 2002 Isolation and expression analysis of the isopropylmalate synthase gene family of Arabidopsis thaliana. J. Exp. Bot. 53: 2453-2454.

Kaan T, Homuth G, Mader U, Bandow J, Schweder T 2002 Genome-wide transcriptional profiling of the Bacillus subtilis cold-shock response. Microbiology 148: 3441-3455.

Kanamori K, Ross BD, Kondrat RW 1998 Rate of glutamate synthesis from leucine in rat brain measured in vivo by 15N NMR. J. Neurochem. 70: 1304-1315.

Karppinen K, Hokkanen J, Tolonen A, Mattila S, Hohtola A 2007 Biosynthesis of hyperforin and adhyperforin from amino acid precursors in shoot cultures of Hypericum perforatum. Phytochemistry 68: 1038-1045.

Kato H, Takeuchi Y, Tsumuraya Y, Hashimoto Y, Nakano H, Kovac P 2003 In vitro biosynthesis of galactans by membrane-bound galactosyltransferase from radish (Raphanus sativus L.) seedlings. Planta 217: 271-282.

Kikuchi A, Edashige Y, Ishii T, Fujii T, Satoh S 1996 Variations in the structure of neutral sugar chains in the pectic polysaccharides of morphologically different carrot calli and correlations with the size of cell clusters. Planta 198: 634-639.

Klipp E, Liebermeister W, Wierling C 2004 Inferring dynamic properties of biochemical reaction networks from structural knowledge. Genome Inform. 15: 125-137.

Kokoeva MV, Storch KF, Klein C, Oesterhelt D 2002 A novel mode of sensory transduction in archaea: binding protein-mediated chemotaxis towards osmoprotectants and amino acids. EMBO J. 21: 2312-2322.

Kroumova AB, Wagner GJ 2003 Different elongation pathways in the biosynthesis of acyl groups of trichome exudate sugar esters from various solanaceous plants. Planta 216: 1013-1021.

Kroumova AB, Xie Z, Wagner GJ 1994 A pathway for the biosynthesis of straight and branched, odd- and even-length, medium-chain fatty acids in plants. Proc. Natl. Acad. Sci. U.S.A. 91: 11437-11441.

Kunisawa T 2003 Gene arrangements and branching orders of gram-positive bacteria. J. Theor. Biol. 222: 495-503.

Kuramitsu S, Ogawa T, Ogawa H, Kagamiyama H 1985 Branched-chain amino acid aminotransferase of Escherichia coli: nucleotide sequence of the ilvE gene and the deduced amino acid sequence. J. Biochem. (Tokyo) 97: 993-999.

Lange PR, Eastmond PJ, Madagan K, Graham IA 2004 An Arabidopsis mutant disrupted in valine catabolism is also compromised in peroxisomal fatty acid beta-oxidation. FEBS Lett. 571: 147-153.

LaRossa RA, Van Dyk TK, Smulski DR 1987 Toxic accumulation of alpha-ketobutyrate caused by inhibition of the branched-chain amino acid biosynthetic enzyme acetolactate synthase in Salmonella typhimurium. J. Bacteriol. 169: 1372-1378.

Lau J, Fu H, Cane DE, Khosla C 1999 Dissecting the role of acyltransferase domains of modular polyketide synthases in the choice and stereochemical fate of extender units. Biochemistry 38: 1643-1651.

Leboeuf E, Thoiron S, Lahaye M 2004 Physico-chemical characteristics of cell walls from Arabidopsis thaliana microcalli showing different adhesion strengths. J. Exp. Bot. 55: 2087-2097.

Lee CP, Eubel H, O'Toole N, Millar AH 2008 Heterogeneity of the mitochondrial proteome for photosynthetic and non-photosynthetic Arabidopsis metabolism. Mol. Cell. Proteomics 7: 1297-1316.

Libessart N, Maddelein ML, Koornhuyse N, Decq A, Delrue B, Mouille G, D'Hulst C, Ball S 1995 Storage, photosynthesis, and growth: the conditional nature of mutations affecting starch synthesis and structure in Chlamydomonas. Plant Cell 7: 1117-1127.

Limberg G, Klaffke W, Thiem J 1995 Conversion of aldonic acids to their corresponding 2-keto-3-deoxy-analogs by the non-carbohydrate enzyme dihydroxy acid dehydratase (DHAD). Bioorg. Med. Chem. 3: 487-494.

Liu H, Reynolds KA 2001 Precursor supply for polyketide biosynthesis: the role of crotonyl-CoA reductase. Metab. Eng. 3: 40-48.

Lucas KA, Filley JR, Erb JM, Graybill ER, Hawes JW 2007 Peroxisomal metabolism of propionic acid and isobutyric acid in plants. J. Biol. Chem. 282: 24980-24989.

Ma QF, Kenyon GL, Markham GD 1990 Specificity of S-adenosylmethionine synthetase for ATP analogues mono- and disubstituted in bridging positions of the polyphosphate chain. Biochemistry 29: 1412-1416.

Malatrasi M, Corradi M, Svensson JT, Close TJ, Gulli M, Marmiroli N 2006 A branched-chain amino acid aminotransferase gene isolated from Hordeum vulgare is differentially regulated by drought stress. Theor. Appl. Genet. 113: 965-976.

Manriquez D, El-Sharkawy I, Flores FB, El-Yahyaoui F, Regad F, Bouzayen M, Latche A, Pech JC 2006 Two highly divergent alcohol dehydrogenases of melon exhibit fruit ripening-specific expression and distinct biochemical characteristics. Plant Mol. Biol. 61: 675-685.

McCourt JA, Pang SS, King-Scott J, Guddat LW, Duggleby RG 2006 Herbicide-binding sites revealed in the structure of plant acetohydroxyacid synthase. Proc. Natl. Acad. Sci. U.S.A. 103: 569-573.

Mehta PK, Hale TI, Christen P 1993 Aminotransferases: demonstration of homology and division into evolutionary subgroups. Eur. J. Biochem. 214: 549-561.

Merkamm M, Chassagnole C, Lindley ND, Guyonvarch A 2003 Ketopantoate reductase activity is only encoded by ilvC in Corynebacterium glutamicum. J. Biotechnol. 104: 253-260.

Metz J 1992 Cobalamin deficiency and the pathogenesis of nervous system disease. Annu. Rev. Nutr. 12: 59-79.

Molhoj M, Verma R, Reiter WD 2003 The biosynthesis of the branched-chain sugar d-apiose in plants: functional cloning and characterization of a UDP-d-apiose/UDP-d-xylose synthase from Arabidopsis. Plant J. 35: 693-703.

Montamat F, Guilloton M, Karst F, Delrot S 1995 Isolation and characterization of a cDNA encoding Arabidopsis thaliana 3-hydroxy-3-methylglutaryl-coenzyme A synthase. Gene 167: 197-201.

Mooney BP, Miernyk JA, Randall DD 2002 The complex fate of alpha-ketoacids. Annu. Rev. Plant Biol. 53: 357-375.

Mrachko GT, Chunduru SK, Calvo KC 1992 The pH dependence of the kinetic parameters of ketol acid reductoisomerase indicates a proton shuttle mechanism for alkyl migration. Arch. Biochem. Biophys. 294: 446-453.

Naik MT, Chang YC, Huang TH 2002 Folding kinetics of the lipoic acid-bearing domain of human mitochondrial branched chain alpha-ketoacid dehydrogenase complex. FEBS Lett. 530: 133-138.

Nandi DL, Lucas SV, Webster LT Jr 1979 Benzoyl-coenzyme A:glycine N-acyltransferase and phenylacetyl-coenzyme A:glycine N-acyltransferase from bovine liver mitochondria. Purification and characterization. J. Biol. Chem. 254: 7230-7237.

Novak L, Loubiere P 2000 The metabolic network of Lactococcus lactis: distribution of 14C-labeled substrates between catabolic and anabolic pathways. J. Bacteriol. 182: 1136-1143.

Nunes FM, Reis A, Silva AM, Domingues MR, Coimbra MA 2008 Rhamnoarabinosyl and rhamnoarabinoarabinosyl side chains as structural features of coffee arabinogalactans. Phytochemistry 69: 1573-1585.

Okuzaki A, Shimizu T, Kaku K, Kawai K, Toriyama K 2007 A novel mutated acetolactate synthase gene conferring specific resistance to pyrimidinyl carboxy herbicides in rice. Plant Mol. Biol. 64: 219-224.

Oldach KH, Peck DM, Cheong J, Williams KJ, Nair RM 2008 Identification of a chemically induced point mutation mediating herbicide tolerance in annual medics (Medicago spp.). Ann. Bot. (Lond.) 101: 997-1005.

Ortega F, Acerenza L 1998 Optimal metabolic control design. J. Theor. Biol. 191: 439-449.

Oue S, Okamoto A, Yano T, Kagamiyama H 2000 Cocrystallization of a mutant aspartate aminotransferase with a C5-dicarboxylic substrate analog: structural comparison with the enzyme-C4-dicarboxylic analog complex. J. Biochem. (Tokyo) 127: 337-343.

Ouellet T, Rutledge RG, Miki BL 1992 Members of the acetohydroxyacid synthase multigene family of Brassica napus have divergent patterns of expression. Plant J. 2: 321-330.

Pang SS, Duggleby RG 1999 Expression, purification, characterization, and reconstitution of the large and small subunits of yeast acetohydroxyacid synthase. Biochemistry 38: 5222-5231.

Paseshnichenko VA 1998 A new alternative non-mevalonate pathway for isoprenoid biosynthesis in eubacteria and plants. Biochemistry (Mosc.) 63: 139-148.

Peters MH, Beltzer JP, Kohlhaw GB 1990 Expression of the yeast LEU4 gene is subject to four different modes of control. Arch. Biochem. Biophys. 276: 294-298.

Pirkov I, Norbeck J, Gustafsson L, Albers E 2008 A complete inventory of all enzymes in the eukaryotic methionine salvage pathway. FEBS J. 275: 4111-4120.

Pittman MS, Kelly DJ 2005 Electron transport through nitrate and nitrite reductases in Campylobacter jejuni. Biochem. Soc. Trans. 33: 190-192.

Platko JV, Willins DA, Calvo JM 1990 The ilvIH operon of Escherichia coli is positively regulated. J. Bacteriol. 172: 4563-4570.

Potter CA, Baumberg S 1996 End-product control of enzymes of branched-chain amino acid biosynthesis in Streptomyces coelicolor. Microbiology 142: 1945-1952.

Radmacher E, Vaitsikova A, Burger U, Krumbach K, Sahm H, Eggeling L 2002 Linking central metabolism with increased pathway flux: L-valine accumulation by Corynebacterium glutamicum. Appl. Environ. Microbiol. 68: 2246-2250.

Rasmusson AG, Soole KL, Elthon TE 2004 Alternative NAD(P)H dehydrogenases of plant mitochondria. Annu. Rev. Plant Biol. 55: 23-39.

Renault P, Godon JJ, Goupil N, Delorme C, Corthier G, Ehrlich SD 1995 Metabolic operons in Lactococci. Dev. Biol. Stand. 85: 431-441.

Ricoult C, Echeverria LO, Cliquet JB, Limami AM 2006 Characterization of alanine aminotransferase (AlaAT) multigene family and hypoxic response in young seedlings of the model legume Medicago truncatula. J. Exp. Bot. 57: 3079-3089.

Robson CA, Vanlerberghe GC 2002 Transgenic plant cells lacking mitochondrial alternative oxidase have increased susceptibility to mitochondria-dependent and -independent pathways of programmed cell death. Plant Physiol. 129: 1908-1920.

Safranek R, Holecek M, Sispera L, Muthny T 2006 Aspects of protein and amino acid metabolism in a model of severe glutamine deficiency in sepsis. Ann. Nutr. Metab. 50: 361-367.

Sahm H, Eggeling L 1999 D-Pantothenate synthesis in Corynebacterium glutamicum and use of panBC and genes encoding L-valine synthesis for D-pantothenate overproduction. Appl. Environ. Microbiol. 65: 1973-1979.

Sahm H, Eggeling L, Morbach S, Eikmanns B 1999 Construction of L-isoleucine overproducing strains of Corynebacterium glutamicum. Naturwissenschaften 86: 33-38.

Saltveit ME, Choi YJ, Tomas-Barberan FA 2005 Mono-carboxylic acids and their salts inhibit wound-induced phenolic accumulation in excised lettuce (Lactuca sativa) leaf tissue. Physiol. Plant. 125: 454-463.

Savvi S, Warner DF, Kana BD, McKinney JD, Mizrahi V, Dawes SS 2008 Functional characterization of a vitamin B12-dependent methylmalonyl pathway in Mycobacterium tuberculosis: implications for propionate metabolism during growth on fatty acids. J. Bacteriol. 190: 3886-3895.

Scaglia F, Carter S, O'Brien WE, Lee B 2004 Effect of alternative pathway therapy on branched chain amino acid metabolism in urea cycle disorder patients. Mol. Genet. Metab. 81: S79-S85.

Schloss JV 2002 Oxygen toxicity from plants to people. Planta 216: 38-43.

Schulz A, Sponemann P, Kocher H, Wengenmayer F 1988 The herbicidally active experimental compound Hoe 704 is a potent inhibitor of the enzyme acetolactate reductoisomerase. FEBS Lett. 238: 375-378.

Schuster J, Binder S 2005 The mitochondrial branched-chain aminotransferase (AtBCAT-1) is capable to initiate degradation of leucine, isoleucine and valine in almost all tissues in Arabidopsis thaliana. Plant Mol. Biol. 57: 241-254.

Schuster J, Knill T, Reichelt M, Gershenzon J, Binder S 2006 BRANCHED-CHAIN AMINOTRANSFERASE4 is part of the chain elongation pathway in the biosynthesis of methionine-derived glucosinolates in Arabidopsis. Plant Cell 18: 2664-2679.

Schwab W, Davidovich-Rikanati R, Lewinsohn E 2008 Biosynthesis of plant-derived flavor compounds. Plant J. 54: 712-732.

Schwender J, Seemann M, Lichtenthaler HK, Rohmer M 1996 Biosynthesis of isoprenoids (carotenoids, sterols, prenyl side-chains of chlorophylls and plastoquinone) via a novel pyruvate/glyceraldehyde 3-phosphate non-mevalonate pathway in the green alga Scenedesmus obliquus. Biochem. J. 316: 73-80.

Scislowski PW, Pickard K 1994 The regulation of transaminative flux of methionine in rat liver mitochondria. Arch. Biochem. Biophys. 314: 412-416.

Self JT, Spencer TE, Johnson GA, Hu JB, Bazer FW, Wu GY 2004 Glutamine synthesis in the developing porcine placental. Biol. Reprod. 70: 1444-1451.

Shaner DL, Singh BK 1993 Phytotoxicity of acetohydroxyacid synthase inhibitors is not due to accumulation of 2-ketobutyrate and/or 2-aminobutyrate. Plant Physiol. 103: 1221-1226.

Shewmaker CK, Boyer CD, Wiesenborn DP, Thompson DB, Boersig MR, Oakes JV, Stalker DM 1994 Expression of Escherichia coli glycogen synthase in the tubers of transgenic potatoes (Solanum tuberosum) results in a highly branched starch. Plant Physiol. 104: 1159-1166.

Shimon LJ, Rabinkov A, Shin I, Miron T, Mirelman D, Wilchek M, Frolow F 2007 Two structures of alliinase from Allium sativum L.: apo form and ternary complex with aminoacrylate reaction intermediate covalently bound to the PLP cofactor. J. Mol. Biol. 366: 611-625.

Singh BK, Shaner DL 1995 Biosynthesis of branched chain amino acids: from test tube to field. Plant Cell 7: 935-944.

Small JR, Kacser H 1993 Responses of metabolic systems to large changes in enzyme activities and effectors. 2. The linear treatment of branched pathways and metabolite concentrations. Assessment of the general non-linear case. Eur. J. Biochem. 213: 625-640.

Small JR, Kacser H 1993 Responses of metabolic systems to large changes in enzyme activities and effectors. 1. The linear treatment of unbranched chains. Eur. J. Biochem. 213: 613-624.

Stevenson DE, Akhtar M, Gani D 1990 L-Methionine decarboxylase from Dryopteris filix-mas: purification, characterization, substrate specificity, abortive transamination of the coenzyme, and stereochemical courses of substrate decarboxylation and coenzyme transamination. Biochemistry 29: 7631-7647.

Stewart C Jr, Kang BC, Liu K, Mazourek M, Moore SL, Yoo EY, Kim BD, Paran I, Jahn MM 2005 The Pun1 gene for pungency in pepper encodes a putative acyltransferase. Plant J. 42: 675-688.

Stewart C Jr, Mazourek M, Stellari GM, O'Connell M, Jahn M 2007 Genetic control of pungency in C. chinense via the Pun1 locus. J. Exp. Bot. 58: 979-991.

Stillman TJ, Migueis AMB, Wang XG, Baker PJ, Britton KL, Engel PC, Rice DW 1999 Insights into the mechanism of domain closure and substrate specificity of glutamate dehydrogenase from clostridium symbiosum. J. Mol. Biol. 285: 875-885.

Suryawan A, Hawes JW, Harris RA, Shimomura Y, Jenkins AE, Hutson SM 1998 A molecular model of human branched-chain amino acid metabolism. Am. J. Clin. Nutr. 68: 72-81.

Szentirmai A, Horvath I 1976 Regulation of branched-chain amino acid biosynthesis. Acta Microbiol. Acad. Sci. Hung. 23: 137-149.

Takahashi N, Yamada T 2000 Pathways for amino acid metabolism by Prevotella intermedia and Prevotella nigrescens. Oral Microbiol. Immunol. 15: 96-102.

Tan S, Evans R, Singh B 2006 Herbicidal inhibitors of amino acid biosynthesis and herbicide-tolerant crops. Amino Acids 30: 195-204.

Taylor NL, Heazlewood JL, Day DA, Millar AH 2004 Lipoic acid-dependent oxidative catabolism of alpha-keto acids in mitochondria provides evidence for branched-chain amino acid catabolism in Arabidopsis. Plant Physiol. 134: 838-848.

Textor S, Wendisch VF, de Graaf AA, Muller U, Linder MI, Linder D, Buckel W 1997 Propionate oxidation in Escherichia coli: evidence for operation of a methylcitrate cycle in bacteria. Arch. Microbiol. 168: 428-436.

Thao ML, Baumann P 1998 Sequence analysis of a DNA fragment from buchnera aphidicola (Aphid endosymbiont) containing the genes dapD-htrA-ilvI-ilvH-ftsL-ftsI-murE. Curr. Microbiol. 37: 214-216.

Torres N, Lopez G, De Santiago S, Hutson SM, Tovar AR 1998 Dietary protein level regulates expression of the mitochondrial branched-chain aminotransferase in rats. J. Nutr. 128: 1368-1375.

Ulvskov P, Wium H, Bruce D, Jorgensen B, Qvist KB, Skjot M, Hepworth D, Borkhardt B, Sorensen SO 2005 Biophysical consequences of remodeling the neutral side chains of rhamnogalacturonan I in tubers of transgenic potatoes. Planta 220: 609-620.

Utsumi Y, Nakamura Y 2006 Structural and enzymatic characterization of the isoamylase1 homo-oligomer and the isoamylase1-isoamylase2 hetero-oligomer from rice endosperm. Planta 225: 75-87.

van der Hoeven RS, Steffens JC 2000 Biosynthesis and elongation of short- and medium-chain-length fatty acids. Plant Physiol. 122: 275-282.

van der Sluis C, Wolken WAM, Giuseppin MLF, Tramper J, Wijffels RH 2000 Effect of threonine, cystathionine, and the branched-chain amino acids on the metabolism of Zygosaccharomyces rouxii. Enz. & Microbial Technol. 26: 292-300.

Van Dyk TK, Ayers BL, Morgan RW, Larossa RA 1998 Constricted flux through the branched-chain amino acid biosynthetic enzyme acetolactate synthase triggers elevated expression of genes regulated by rpoS and internal acidification. J. Bacteriol. 180: 785-792.

Velasco JA, Cansado J, Pena MC, Kawakami T, Laborda J, Notario V 1993 Cloning of the dihydroxyacid dehydratase-encoding gene (ILV3) from Saccharomyces cerevisiae. Gene 137: 179-185.

Vermeer CP, Nastold P, Jetter R 2003 Homologous very-long-chain 1,3-alkanediols and 3-hydroxyaldehydes in leaf cuticular waxes of Ricinus communis L. Phytochemistry 62: 433-438.

Vikso-Nielsen A, Blennow A, Hamborg Nielsen T, Lindberg Moller B 1998 Phosphorylated alpha(1-->4)glucans as substrate for potato starch-branching enzyme I. Plant Physiol. 117: 869-875.

Vogg G, Fischer S, Leide J, Emmanuel E, Jetter R, Levy AA, Riederer M 2004 Tomato fruit cuticular waxes and their effects on transpiration barrier properties: functional characterization of a mutant deficient in a very-long-chain fatty acid beta-ketoacyl-CoA synthase. J. Exp. Bot. 55: 1401-1410.

Wallbrandt P, Tegman V, Jonsson BH, Wieslander A 1992 Identification and analysis of the genes coding for the putative pyruvate dehydrogenase enzyme complex in Acholeplasma laidlawii. J. Bacteriol. 174: 1388-1396.

Walton JD 2006 HC-toxin. Phytochemistry 67: 1406-1413.

Wang D, Hu Y, Zheng F, Zhou K, Kohlhaw GB 1997 Evidence that intramolecular interactions are involved in masking the activation domain of transcriptional activator Leu3p. J. Biol. Chem. 272: 19383-19392.

Weigelt K, Kuster H, Radchuk R, Muller M, Weichert H, Fait A, Fernie AR, Saalbach I, Weber H 2008 Increasing amino acid supply in pea embryos reveals specific interactions of N and C metabolism and highlights the importance of mitochondrial metabolism. Plant J. May 20 [Epub ahead of print].

Whalen WA, Berg CM 1982 Analysis of an avtA::Mu d1(Ap lac) mutant: metabolic role of transaminase C. J. Bacteriol. 150: 739-746.

Wu G 1998 Intestinal mucosal amino acid catabolism. J. Nutr. 128: 1249-1252.

Xiao W, Rank GH 1990 Branched chain amino acid regulation of the ILV2 locus in Saccharomyces cerevisiae. Genome 33: 596-603.

Yahyaoui FE, Wongs-Aree C, Latche A, Hackett R, Grierson D, Pech JC 2002 Molecular and biochemical characteristics of a gene encoding an alcohol acyl-transferase involved in the generation of aroma volatile esters during melon ripening. Eur. J. Biochem. 269: 2359-2366.

Yang JH, Kim SS 1993 Purification and characterization of the valine sensitive acetolactate synthase from Serratia marcescens ATCC 25419. Biochim. Biophys. Acta 1157: 178-184.

Yennawar NH, Islam MM, Conway M, Wallin R, Hutson SM 2006 Human mitochondrial branched chain aminotransferase isozyme: structural role of the CXXC center in catalysis. J. Biol. Chem. 281: 39660-39671.

Zabalza A, Gaston S, Ribas-Carbo M, Orcaray L, Igal M, Royuela M 2006 Nitrogen assimilation studies using (15)N in soybean plants treated with imazethapyr, an inhibitor of branched-chain amino acid biosynthesis. J. Agric. Food Chem. 54: 8818-8823.

Zeeman SC, Smith SM, Smith AM 2007 The diurnal metabolism of leaf starch. Biochem. J. 401: 13-28.

Zelenaya-Troitskaya O, Perlman PS, Butow RA 1995 An enzyme in yeast mitochondria that catalyzes a step in branched-chain amino acid biosynthesis also functions in mitochondrial DNA stability. EMBO J. 14: 3268-3276.

Zhang Y, Dickinson JR, Paul MJ, Halford NG 2003 Molecular cloning of an Arabidopsis homologue of GCN2, a protein kinase involved in co-ordinated response to amino acid starvation. Planta 217: 668-675.

Zhao J, Williams CC, Last RL 1998 Induction of Arabidopsis tryptophan pathway enzymes and camalexin by amino acid starvation, oxidative stress, and an abiotic elicitor. Plant Cell 10: 359-370.

Zhao P, Inoue K, Kouno I, Yamamoto H 2003 Characterization of leachianone G 2"-dimethylallyltransferase, a novel prenyl side-chain elongation enzyme for the formation of the lavandulyl group of sophoraflavanone G in Sophora flavescens Ait. cell suspension cultures. Plant Physiol. 133: 1306-1313.

Zhou KM, Kohlhaw GB 1990 Transcriptional activator LEU3 of yeast. Mapping of the transcriptional activation function and significance of activation domain tryptophans. J. Biol. Chem. 265: 17409-17412.

Zykwinska AW, Ralet MC, Garnier CD, Thibault JF 2005 Evidence for in vitro binding of pectin side chains to cellulose. Plant Physiol. 139: 397-407.

Number of references = 194